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Esoterique and Make Believe will represent Andre Fabre in the Breeders' Cup Mile at Keeneland.
The five-year-old mare Esoterique has taken her form to a new level this season, winning the Prix Jacques le Marois and the Sun Chariot Stakes.
Make Believe beat stablemate New Bay in the French 2000 Guineas before disappointing at Royal Ascot behind Gleneagles.
He was not seen again until Arc weekend when he blitzed a good field in the Prix de la Foret over seven furlongs.
Fabre's inmates will be joined on the flight to Kentucky by Miss France, who runs in the Filly & Mare Turf.
The four-year-old won the 1000 Guineas at Newmarket last year but injury has restricted her to just two late-season outings this year, finishing second twice.
Fabre said: "I will take three to the Breeders' Cup. Miss France will run in the Filly & Mare and Esoterique and Make Believe will run in the Mile.
"I think they (Esoterique and Make Believe) would both have a good chance.
"Esoterique's form this season is very good indeed, but Make Believe has won two Group Ones also - I have two great chances."
Fabre will be hoping for better luck than he had at Ascot on Champions Day where Vadamos and Territories disappointed in the Champion Stakes and QEII respectively.
"Vadamos ran as if he was out of control - early on I knew he had no chance," said Fabre.
"Territories was a bit disappointing and he probably needed the race. He also had no cover. He'll stay in training next year.
"It was a sad day, especially with what happened in the rugby."